Frequently Asked Questions

Alflorex para Irritable Colon is a medical device containing the unique strain 35624 of Bifidobacterium longum, which has clinically shown its effectiveness against all symptoms of the irritable bowel. Each capsule of Alflorex contains one billion bacteria (1x109).

Alflorex has been jointly researched and developed by scientists, clinicians and gastroenterologists from Alimentary Health Ltd. and University College Cork in Ireland, one of the world"s leading institutions in probiotic research.

35624 is the name of the trademark registered by Alimentary Health for the probiotic strain Bifidobacterium longum 35624. A strain that has been shown to be effective in treating symptoms associated with Irritable Bowel Syndrome (IBS).

Not all strains of the same family have the same effects on the body, nor are they all beneficial. The 35624 strain has more than 20 years of scientific research, more than 75 publications, a significant history of consumption for more than 15 years and is the No. 1 of the most recommended probiotics by gastroenterologists in the US.

Yes. Alflorex for IBS contains strain 35624 of Bifidobacterium longum, a living bacterial strain found naturally in the human gut. It belongs to the Bifidobacterium family of bacteria, which mothers transmit to their babies at birth.

To ensure that this natural strain reaches the gut alive and addresses symptoms of the irritable colon, a stable and easy-to-take formulation has been developed. This stable formulation also ensures that Alflorex para Colon Irritable does not need refrigeration.

Alflorex is the only product in Europe that contains the unique 35624 live bacterial culture, for the specific treatment of symptoms of the irritable bowel.

This culture has been clinically tested by leading scientists and gastroenterologists. The results of these trials have been published in a wide range of respected scientific journals.

The live 35624 culture in Alflorex is a type of bacteria that occurs naturally in the human gut. It"s part of the Bifidobacterium group, one of the first kinds of bacteria passed by mothers to their babies at birth.

A single Alflorex capsule contains around 1 billion live bacteria, or 1x109 colony forming units (CFUs), at the time of manufacture. 

The quantity of bacteria provided in each capsule has been chosen for optimal balance in the gut. The dose in the capsule remains effective throughout its shelf life.

Yes. The 35624 culture in Alflorex for IBS has been shown in 4 clinical trials, reported in respected scientific publications, to remain active right through the digestive system and to reach the bowel with its properties intact.

Alflorex for IBS is especially indicated in the treatment of typical symptoms of the Irritable Bowel: bloating, flatulence, abdominal pain, constipation and/or diarrhea.

Alflorex for IBS acts immediately and begins to prime your gut when it is needed. This activity takes approximately 4 weeks*. It is important to take Alflorex every day.

Some people may experience mild and temporary changes in their gut during this first 4 weeks as Alflorex begins to gently prime the gut. If you have any questions at all about how Alflorex is working for you, please contact us.

*In rare cases it may take Alflorex longer than 4 weeks to prime the gut, possibly up to 8 weeks. If you"d like to talk about this and taking Alflorex, please contact us.

The 35624 live culture is part the Bifidobacterium family, one of the first kinds of bacteria passed by mothers to their babies at birth. Hence it is at home in the human gut.

Initial symptoms relief is observed approximately after 1-2 weeks of taking Alflorex for IBS on a regular basis. Rarely, Alflorex may require more than 1 month to readjust the intestine, even up to 2-3 months.

Some people may experience mild and temporary changes in their gut during the first 4 weeks as Alflorex begins to gently prime the gut. It is recommended not to stop taking it. 

If you have any questions at all about how Alflorex is working for you, please contact us.

Whenever you like. It is not important the time of the day when you take Alflorex. The most important thing is to take it daily. It is recommended to take Alflorex as a lifestyle routine, when it is easier to remember your take. It can be taken with or without food.

An Alflorex capsule is a size 3 capsule, one of the smallest sizes available.

Take 1 capsule a day, with or without food, at any time of the day.

Alflorex for IBS capsules have been formulated to be swallowed whole, with water, milk or non-acid juices. If there is difficulty swallowing, the capsules can be opened and mixed with the cold or temperate food or drink to be consumed immediately. Emptying the contents in a hot food or drink is not recommended.

If you miss a day taking your dose, you do not need to double it the next day. Continue with the indicated 1 capsule per day.

Alflorex IBS should be taken daily. The 35624 live bacterial culture in Alflorex stays in your gut for as long as you continue to take the product. It performs its action in the gut and then will naturally be swept out by regular bowel movements.

The recommendation is to take Alflorex for 4 weeks to prepare the intestine and then continue taking it daily to maintain its effect. Very rarely has the strain 35624 needed more than 4 weeks to prepare the gut, but it can reach up to 8-12 weeks.

By taking a single capsule of Alflorex every day you can ensure your gut remains primed.

Fruit juices are generally acidic, and acid can damage the 35624 culture, making it less effective. So, we recommend taking Alflorex for IBS with water or milk or less acidic drinks like soya, almond or rice milks.

However, Alflorex for IBS can be taken as part of a meal that has fruit juice, as the food will help protect the Alflorex culture.

Like any living microorganism, the active strain of Alflorex for IBS, Bifidobacterium longum 35624, can be inactivated by alcohol. 

We recommend not drinking alcohol at the same time or for a few hours after taking Alflorex for IBS.

Alflorex for IBS does not carry titanium dioxide or any other dye.

Yes. There are no known allergens in Alflorex for IBS. 

Alflorex for IBS DOES NOT CONTAIN gluten, milk or dairy derivatives, soy, sugar, sweeteners, preservatives or dyes. It is indicated for patients with lactose intolerance, dairy derivatives or soya allergies.

All raw materials used for Alflorex for IBS do not contain any allergen listed in the Directive 2007/68/EC and its amendments. The facilities we use to manufacture also ensure that during the production process, raw materials are not exposed to allergens cross contamination.

Yes. Each capsule contains only a residual amount of sugar and does not affect blood glucose levels.

Yes.

Yes.

No. It just needs to be stored at under 25^oC and in a dry environment.

Alflorex for IBS has been carefully formulated to be stable at room temperature and does not need to be refrigerated.

The special packaging for Alflorex for IBS capsules means that they can travel with you and keep their qualities.

Alflorex for IBS costs less than €1 per day and enables you to regain control of your gut health.

In Spain, Alflorex for IBS is available in pharmacies. You can purchase it without a prescription.

If Alflorex is not available on the shelf, the pharmacist can order it immediately and receive it in a few hours.

You can also order it through online pharmacies.

The 35624 strain of Bifidobacterium longum is well tolerated. 

Alflorex for IBS has been used for more than 15 years by tens of thousands of consumers in the United States, Canada and Europe. Because of its presence on the QPS (Qualified Safety Presumption) list, the bacterial strain of Alflorex for IBS is recognized as safe by the European Agency EFSA (European Food Safety Authority).

The 35624 culture in Alflorex has been studied by doctors and scientists in well run clinical trials. No safety concerns were identified. The safety of the product has also been confirmed in scientific reviews.

The 35624 bacteria are part of the Bifidobacterium family of bacteria, one of the first types of bacteria from mothers to their babies at birth.

There are no known side effects with Alflorex.

Some people may experience mild and temporary changes in their gut during the first 4 weeks as Alflorex for IBS begins to gently prime the gut.

No side effects in conjunction with the use of Alflorex for IBS have been observed to date.

There are no known interactions with any medications. However, Alflorex for IBS is composed of bacteria that, like any probiotic, can be destroyed by simultaneous intake with antibiotics, so it is advisable to separate the time of day to take one and the other product.

On the other hand, if you have a serious or chronic illness, if you are wondering if Alflorex for Irritable Colon is right for you, or if you have any questions about using Alflorex for Colon Irritable with medications, seek advice from your doctor or pharmacist.

As happens with most bacterial cultures, a dose of antibiotics could inactivate the bacterial culture in Alflorex. If you are prescribed a course of antibiotics, we advise that you take the dose of the antibiotic at a different time of day to when you take your daily Alflorex.

Yes. Alflorex for IBS can be taken with all or any of these products. To date, there are no known interactions of Alflorex with dietary supplements or medicines.

There is no evidence available that Alflorex capsules should not be used during pregnancy and breast-feeding.

Alflorex for IBS contains strain 35624 of Bifidobacterium longum, a probiotic strain that is part of the bifidobacteria family that mothers transmit to their babies at birth and are also present in breast milk. These species are the first to colonize the newborn"s intestine.

There are no clinical studies to support the efficacy of Alflorex for IBS in Crohn"s disease or Ulcerative Colitis.

If in doubt before taking Alflorex for IBS, consult a doctor or health care professional.

PrecisionBiotic cultures are unique bacterial cultures that have been specifically researched and rigorously tested by scientists at PrecisionBiotics Ltd.

All products contain bacteria that occur naturally in the human gut and are at home there.

PrecisionBiotics spend many years observing and testing them in real people to ensure they have the precise features needed and that they meet our rigorous safety standards.

To ensure that they reach the gut in optimal conditions, PrecisionBiotics™ has created special formulations and confirmed its activity in the gut, meeting the highest requirements for scientific testing and clinical trials in humans. These formulations are stable and therefore ensure that none of the products containing them need refrigeration.

PrecisionBiotics means specific bacteria, in the right amount.

Yogurts are made by fermenting milk with lactic acid-producing bacterial cultures, such as Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus (starting cultures) that are added during the manufacturing process.

The starting strains used in these fermentation processes to make yogurts are not native to the human gut and have not been tested in clinical trials.

Many yoghurts contain live bacterial cultures, but these are usually chosen to make good yoghurt, not for their activity in the human gut. If bacterial cultures have been added during the manufacturing process, they may not be cultures that have been tested in clinical trials or that are native to the human gut.

In contrast, the 35624 culture of Alflorex for IBS is a highly specialized strain that has been isolated from the human gut, and which by scientific methods has been selected to obtain a targeted therapeutic action.

We"re sometimes asked why PrecisionBiotics products contain only one or two types of bacteria, instead of a mix of five or even ten types.

As scientists, we know that mixing multiple bacterial cultures can mean their individual features are affected. Different cultures behave in different ways and may even have competing effects. Cultures of animal or plant origin may not be native to the human gut, so we do not add them.

It is the specific culture of bacteria and how that culture interacts with your unique gut bacteria that determines whether you will notice a difference.

So, PrecisionBiotics focus is on investing to find the best bacterial culture for each specific gut action. We then put each culture through a rigorous series of tests, culminating in clinical trials in the UK and Europe.

They produce a pure formulation, with no added bulk yoghurt or animal cultures, to provide a PrecisionBiotic product that they can guarantee and that clinicians can recommend.

They also guarantee that the number of bacteria is the optimal amount for each PrecisionBiotic product and how it works in the human gut.

The term probiotic is a word meaning "pro-life".

On this base, probiotics have been defined as "living microorganisms that confer a health benefit for the body when administered in adequate amounts".

Probiotics are increasingly used and evaluated on digestive balance function. Many clinical studies demonstrate the importance of probiotics in improving gut health and for stimulating immune function.

However, different probiotics can also have different benefits. Studies investigating the health effects of probiotics have been documented in areas such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBD), vaginal infections, immune enhancement, atopic eczema, rheumatoid arthritis and liver cirrhosis.

Prebiotics are non-digestible dietary ingredients, whose function is to stimulate the growth or activity of some bacteria of the gut microbiota, resulting in a health benefit.

Symbiotic is the combination of probiotics and prebiotics.